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KMID : 0390620130210020064
Journal of Cardiovascular Ultrasound
2013 Volume.21 No. 2 p.64 ~ p.71
Feasibility of Real-Time Three-Dimensional Echocardiography for the Assessment of Distorted Biventricular Systolic Function in Patients with Cor Pulmonale
Cho Jung-Sun

Youn Ho-Joong
Cho Eun-Joo
Her Sung-Ho
Park Mahn-Won
Lee Jae-Beum
Choi Min-Seok
Park Chan-Seok
Abstract
Background:This study was to investigate the feasibility of real-time 3-dimensional echocardiography (RT3DE) for the analysis of biventricular ejection fractions and volume measurements in patients with cor pulmonale and the correlations of RT3DE results with 64-slice multi-detector cardiac computed tomography (64-MDCT) results.

Methods:This study included a total of 22 patients (59.3 ¡¾ 16.6 years of age; 10 males and 12 females) who showed flattening or reverse curvature of the interventricular septum and severe pulmonary hypertension [mean right ventricular (RV) systolic pressure = 66.8 ¡¾ 19.7 mmHg] on 2-dimensional transthoracic echocardiography due to cor pulmonale. Biventricular enddiastolic and end-systolic volumes were measured by RT3DE and 64-MDCT. The severity of D-shaped deformation was evaluated by using left ventricular (LV) eccentricity index (ratio of diameters parallel/perpendicular to the interventricular septum on parasternal short axis images of the papillary muscle level).

Results:There were moderate correlations between biventricular volumes measured by RT3DE and 64-MDCT except for LV end-systolic volume (59.8 ¡¾ 17.1 vs. 73.2 ¡¾ 20.2 mL, r = 0.652, p = 0.001 for LV end-diastolic volume; 30.6 ¡¾ 9.1 vs. 30.8 ¡¾ 12.5 mL, r = 0.361, p = 0.099 for LV end-systolic volume; 110.1 ¡¾ 42.9 vs. 171.1 ¡¾ 55.3 mL, r = 0.545, p = 0.009 for RV enddiastolic volume; and 80.9 ¡¾ 35.0 vs. 128.7 ¡¾ 45.1 mL, r = 0.549, p = 0.005 for RV end-systolic volume respectively).

Conclusion:This study suggests that RT3DE may be a modest method for measuring distorted biventricular end-systolic and end-diastolic volumes in patients with cor pulmonale.
KEYWORD
Real-time three-dimensional echocardiography , 64-slice multi-detector cardiac computed tomography , Severe pulmonary hypertension , D-shaped deformation , Cor pulmonale
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